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$SYRE
Aeglea BioTherapeutics, Inc., a clinical-stage biotechnology company, designs and develops human enzyme therapeutics for the treatment of patients and families with rare metabolic diseases. The company's lead product candidate is pegzilarginase, a recombinant human Arginase 1 that is in Phase III PEACE trial to evaluate the safety and efficacy for the treatment of Arginase 1 deficiency. It also develops AGLE-177, a polyethylene glycol modified, which is in Phase I/II clinical trial for the treatment of patient with homocystinuria. In addition, the company's preclinical pipeline includes AGLE-325 for the treatment of cystinuria, as well as other research programs. The company was formerly known as Aeglea BioTherapeutics Holdings, LLC and changed its name to Aeglea BioTherapeutics, Inc. in March 2015. Aeglea BioTherapeutics, Inc. was founded in 2013 and is headquartered in Austin, Texas.
Healthcare
Sector
Biotechnology
Industry
Jonathan D. Alspaugh
CEO
69
Employees
$73.50
Current Price
$48.63M
Market Cap
52W Low$13.93
Current$73.5091.8% above low, 8.2% below high
52W High$78.80

Insider Activity Statistics

Aggregated buying and selling activity by time period
PeriodTypeInsidersTransactionsValueSharesBuy/Sell Ratio
1 weekBuys00---
Sells00--
2 weeksBuys00---
Sells00--
1 monthBuys00--All Sells
Sells418$13,515,383.59185,833
2 monthsBuys00--All Sells
Sells423$15,023,271.91216,291
3 monthsBuys00--All Sells
Sells427$15,757,757.91233,791
See activity going back 12 months โ€” create a free account

Insider Transactions

Recent purchases and sales by company insiders
DateInsiderTypeSharesPriceValueActions
May 8, 2026
HENDERSON MICHAEL THOMAS
Director
Sale33,513$73.72$2,470,578.36View Details
May 8, 2026
HENDERSON MICHAEL THOMAS
Director
Sale2,404$72.57$174,458.28View Details
May 8, 2026
HENDERSON MICHAEL THOMAS
Director
Sale19,269$75.35$1,451,919.15View Details
May 8, 2026
HENDERSON MICHAEL THOMAS
Director
Sale24,814$74.76$1,855,094.64View Details
May 1, 2026
Burrows Scott L
Chief Financial Officer
Sale12,500$71.37$892,125.00View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale10,358$73.74$763,798.92View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale19,656$70.61$1,387,910.16View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale5,059$74.60$377,401.40View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale400$75.37$30,148.00View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale12,777$72.94$931,954.38View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale8,777$71.56$628,082.12View Details
May 1, 2026
Sloan Sheldon
Chief Medical Officer
Sale21,306$69.53$1,481,406.18View Details
May 1, 2026
Turtle Cameron
Director
Sale1,000$71.76$71,760.00View Details
May 1, 2026
Turtle Cameron
Director
Sale5,300$69.54$368,562.00View Details
May 1, 2026
Turtle Cameron
Director
Sale1,700$74.23$126,191.00View Details
May 1, 2026
Turtle Cameron
Director
Sale3,100$73.14$226,734.00View Details
May 1, 2026
Turtle Cameron
Director
Sale3,600$70.77$254,772.00View Details
May 1, 2026
Turtle Cameron
Director
Sale300$74.96$22,488.00View Details
Apr 1, 2026
Turtle Cameron
Director
Sale2,656$49.92$132,587.52View Details
Apr 1, 2026
Turtle Cameron
Director
Sale12,344$49.20$607,324.80View Details

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